The letter is addressed to Dr. J.R. Moore in Galveston Texas. The letter narrates the story of a private citizen who travels while being serious ill. The unnamed passenger caught a cold in winter while taking a Turkish bath while being unprepared. He continued to travel despite severe symptoms. While traveling he drove throughout the Texas countryside in car with no insulation from the extreme weather and was exposed to the cold for lengthy durations. His symptoms continued to worsen. While traveling by train one day the passenger received a severe jolt from cargo being attached to the train. Later he would blame an anasarca peritoneal cavity on the jolt he received while riding the train. Doctor Jameson is asking Doctor Moore if the anasarca peritoneal cavity, essentially a cavity of bacterial fluid within the abdominal sac, could have been caused by the jolt or whether it was more likely caused by the several days exposure to the elements. Doctor Jameson is probably inquiring as to the possible causes of the sickness to prepare for possible mal practice litigation.